Cigarette smoking, cutaneous vasculature, and tissue oxygen

  • Yung-Hian Leow
    Department of Dermatology, University of California, School of Medicine, San Francisco, California, USA
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  • Howard I Maibach
    Address correspondence to Howard I. Maibach, M.D., Department of Dermatology, University of California, School of Medicine, Box 0989, Surge 110, San Francisco, CA 94131-0989
    Department of Dermatology, University of California, School of Medicine, San Francisco, California, USA
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      Smoking is an established risk factor for cardiovascular diseases, chronic obstructive lung diseases, and pulmonary malignancies. The association of smoking with cutaneous morbidity and mortality was recently emphasized by Smith and Fenske.
      • Smith J.B
      • Fenske N.A
      Cutaneous manifestations and consequences of smoking.
      We review here the clinical significance and experimental evidence of smoking and the skin. Use of bioengineering techniques and possible underlying mechanisms for changes occurring in the microcirculation and tissue oxygen will also be discussed.
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