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Cigarette smoking, cutaneous vasculature, and tissue oxygen

  • Yung-Hian Leow
    Affiliations
    Department of Dermatology, University of California, School of Medicine, San Francisco, California, USA
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  • Howard I Maibach
    Correspondence
    Address correspondence to Howard I. Maibach, M.D., Department of Dermatology, University of California, School of Medicine, Box 0989, Surge 110, San Francisco, CA 94131-0989
    Affiliations
    Department of Dermatology, University of California, School of Medicine, San Francisco, California, USA
    Search for articles by this author
      Smoking is an established risk factor for cardiovascular diseases, chronic obstructive lung diseases, and pulmonary malignancies. The association of smoking with cutaneous morbidity and mortality was recently emphasized by Smith and Fenske.
      • Smith J.B
      • Fenske N.A
      Cutaneous manifestations and consequences of smoking.
      We review here the clinical significance and experimental evidence of smoking and the skin. Use of bioengineering techniques and possible underlying mechanisms for changes occurring in the microcirculation and tissue oxygen will also be discussed.
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      References

        • Smith J.B
        • Fenske N.A
        Cutaneous manifestations and consequences of smoking.
        J Am Acad Dermatol. 1996; 34: 717-732
        • Mosely L.H
        • Finseth F
        Cigarette smoking.
        Hand. 1977; 98: 97-101
        • Mosely L.H
        • Finseth F
        • Goody M
        Nicotine and its effects on wound healing.
        Plast Reconstr Surg. 1978; 61: 570-575
        • Lawrence W.T
        • Morphy R.C
        • Robson M.C
        • et al.
        The detrimental effect of cigarette smoking on flap survival.
        Br J Plast Surg. 1984; 37: 216-219
        • Craig S
        • Rees T.D
        The effects of smoking on experimental skin flaps in hamsters.
        Plast Reconstr Surg. 1985; 75: 842-846
        • Nolan J
        • Jenkins R.A
        • Kurihara K
        • et al.
        The acute effects of cigarette smoke on experimental skin flaps.
        Plast Reconstr Surg. 1985; 75: 544-549
        • Wilson G.R
        • Jones B.M
        The damaging effect of smoking on digital revascularisation.
        Br J Plast Surg. 1984; 37: 613-614
        • Harris G.D
        • Finseth F
        • Buncke H.J
        The hazard of cigarette smoking following digital replantation.
        J Microsurg. 1980; 1: 403
        • Rees T.D
        • Liverett D.M
        • Guy C.I
        The effect of cigarette smoking on skin flap survival in the facelift patient.
        Plast Reconstr Surg. 1984; 73: 922-925
        • Riefkohl R
        • Wolfe J.A
        • Cox E.B
        • et al.
        Association between cutaneous occlusive vascular disease, cigarette smoking and skin slough after rhytidectomy.
        Plast Reconstr Surg. 1986; 77: 592-595
        • Dardour J.C
        • Pugash E
        • Aziza R
        The one-stage preauricular flap for male pattern baldness.
        Plast Reconstr Surg. 1988; 81: 907-912
        • Goldminz D
        • Bennet R.G
        Cigarette smoking and flap and full-thickness graft necrosis.
        Arch Dermatol. 1991; 127: 1012-1015
        • Johnston C
        Cigarette smoking and the outcome of human pregnancies.
        Clin Toxicol. 1981; 18: 189-209
        • Bruce J.W
        • Miller J.R
        • Hooker D.R
        The effect of smoking upon the blood pressure and upon the volume of the hand.
        Am J Physiol. 1909; 24: 104
        • Maddock W.G
        • Coller F.A
        Peripheral vasoconstriction by tobacco demonstrated by skin temperature changes.
        Proc Soc Exp Biol Med. 1973; 29: 487
        • Bernardi L
        • Berardesca E
        Measurement of skin blood flow by laser-Doppler flowmetry.
        in: Berardesca E Elsner P Wilhelm K.P Maibach H.I Bioengineering of the skin methods and instrumentation. CRC Press, Boca Raton, FL1995: 13-28
        • Van Adrichem L.N.A
        • Hovius S.E.R
        • Van Der Meulen J.C
        Acute effects of cigarette smoking on microcirculation of the thumb.
        Br J Plast Surg. 1992; 45: 9-11
        • Richardson D.R
        Effects of habitual tobacco smoking on reactive hyperemia in the human hand.
        Arch Environ Health. 1985; 40: 114-119
        • Goodfield M.J.D
        • Hume A
        • Rowell N.R
        The acute effects of cigarette smoking on cutaneous blood flow in smoking and nonsmoking subjects with and without Raynaud’s phenomenon.
        Br J Rheumatol. 1990; 29: 89-91
        • Bornmyr S
        • Svensson H
        Thermography and laser-Doppler flowmetry for monitoring changes in finger skin blood flow upon cigarette smoking.
        Clin Physiol. 1991; 11: 135-141
        • Tur E
        • Yosipovitch G
        • Oren-Vulfs S
        Chronic and acute effects of cigarette smoking on skin blood flow.
        Angiology. 1992; 43: 328-335
        • Baab D.A
        • Oberg P.A
        The effects of cigarette smoking on gingival blood flow in human.
        J Clin Periodontol. 1987; 14: 418-424
        • Lecerof H
        • Bornmyr S
        • Lilja B
        • et al.
        Acute effects of doxazosin and atenolol on smoking-induced peripheral vasoconstriction in hypertensive habitual smokers.
        J Hypertens. 1990; 8: S29-S33
        • Richardson D.R
        Effects of tobacco smoke inhalation on capillary blood flow in human skin.
        Arch Environ Health. 1987; 42: 19-25
        • Saumet J.L
        • Leftheriotis G
        • Dittmar A
        • et al.
        Relationship between pulse amplitude and thermal exchange in the finger.
        Clin Physiol. 1986; 6: 139-146
        • Suter R.W
        • Buzzi R
        • Battig K
        Cardiovascular effects of smoking cigarettes with different nicotine deliveries.
        Psychopharmacology. 1983; 30: 106-112
        • Bounameaux H
        • Griessen M
        • Benedet P
        • et al.
        Nicotine-induced haemodynamic changes during cigarette smoking and nicotine gum chewing.
        Cardiovasc Res. 1988; 22: 154-158
        • Netscher D.T
        • Wigoda P
        • Thornby J
        • et al.
        The hemodynamic and hematologic effects of cigarette smoking versus a nicotine patch.
        Plast Reconstr Surg. 1995; 96: 681-688
        • Ahlsten G
        • Ewald U
        • Tuvemo T
        Impaired vascular reactivity in newborn infants of smoking mother.
        Acta Paediatr Scand. 1987; 76: 248-253
        • Jensen J.A
        • Goodson W.H
        • Hopf H.W
        • et al.
        Cigarette smoking decreases tissue oxygen.
        Arch Surg. 1991; 126: 1131-1134
        • Tur E
        Cutaneous laser Doppler flowmetry in general medicine.
        in: Beredesca E Elsner P Maibach H.I Bioengineering of the skin Cutaneous blood flow and erythema. CRC Press, Boca Raton, FL1995: 133-153
        • Benowitz N.L
        Pharmacologic aspects of cigarette smoking and nicotine addiciton.
        N Engl J Med. 1988; 319: 1318-1330
        • Herning R.I
        • Jones R.T
        • Benowitz N.L
        • et al.
        How a cigarette is smoked determines blood nicotine levels.
        Clin Pharmacol Ther. 1983; 33: 84-90
        • Alster P
        • Berlin T
        • Boliman S.O
        • et al.
        Nicotine inhibits prostaglandin synthesis in human kidney microsomes.
        Acta Physiol Scand. 1983; 117: 581-583
        • Levine P.H
        An acute effect of cigarette smoking on platelet function.
        Circulation. 1973; 48: 619-623
        • Dadak C
        • Leithner C
        • Sinzinger H
        • et al.
        Diminished prostacyclin formation in umbilical arteries of babies born to women who smoke.
        Lancet. 1981; i: 94
        • Ahlsten G
        • Ewald U
        • Tuveno T
        Maternal smoking reduces prostacyclin formation in human umbilical arteries.
        Acta Obstet Gynecol Scand. 1986; 65: 645-649
        • Nadler J.L
        • Velasco J.S
        • Horton R
        Cigarette smoking inhibits prostacyclin formation.
        Lancet. 1983; 1: 1248-1250
        • Rowe J.W
        • Kilgove A
        • Robertson G.L
        Evidence in man that cigarette smoking induces vasopressin release via an airway-specific mechanism.
        J Clin Endocrinol Metab. 1980; 51: 170-172
        • Husain M.K
        • Frautz A.G
        • Ciarochi F
        • et al.
        Nicotine-stimulated release of neurophysin and vasopressin in humans.
        J Clin Endocrinol Metab. 1975; 41: 1113-1117
        • Waeber B
        • Schaller M.D
        • Nussberger J
        • et al.
        Skin blood flow reduction induced by cigarette smoking.
        Am J Physiol. 1984; 247: H895-H901
        • Cryer P.E
        • Haymond M.W
        • Santiago J.V
        • et al.
        Norepinephrine and epinephrine release and adrenergic mediation of smoking-associated hemodynamic and metabolic events.
        N Engl J Med. 1976; 295: 573-577
        • Nicito-Mauro V
        Smoking, calcium, calcium antagonists, and aging.
        Exp Gerontol. 1990; 25: 393-399
        • Belch J.J
        • McArdle B.M
        • Burns P
        • et al.
        The effects of acute smoking on platelet behaviour, fibrinolysis and haemorrhage in habitual smokers.
        Thromb haemost. 1984; 51: 6-8
        • Davis J.W
        • Shelton L
        • Eigenberg D.A
        • et al.
        Effects of tobacco and non-tobacco cigarette smoking on endothelium and platelets.
        Clin Pharmacol Ther. 1985; 37: 529-533
        • Model D
        Smoker’s face.
        Br Med J. 1985; 291: 1760-1762