Abstract
Dysesthesia is symptomatology that includes, but is not limited to, sensations of
pain, burning, crawling, biting, numbness, piercing, pulling, cold, shock-like, pulling,
wetness, and heat. These sensations can cause significant emotional distress and functional
impairment in affected individuals. While some cases of dysesthesias are secondary
to organic etiologies, most cases exist without an identifiable infectious, inflammatory,
autoimmune, metabolic, or neoplastic process. Ongoing vigilance is required for concurrent
or evolving processes, including paraneoplastic presentations. Elusive etiologies,
unclear treatment regimens, and stigmata leave patients and clinicians with a difficult
path forward marked by “doctor shopping,” lack of treatment, and significant psychosocial
distress. We addresses this symptomatology and the psychosocial burden that often
comes with it. Although notoriously labeled as "difficult to treat," dysesthesia patients
can be effectively managed, making life-changing relief possible for patients.
Keywords
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Article info
Publication history
Publication stage
In Press Accepted ManuscriptFootnotes
Funding Sources: None.
Declaration of Competing Interest: None declared.
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© 2023 Published by Elsevier Inc.
