Abstract
Subacute cutaneous lupus erythematosus (SCLE) is a photosensitive dermatosis characterized
by a nonscarring papulosquamous eruption and specific antibodies in the patient's
serum. Genetic and environmental factors represent the leading causes of SCLE; however,
several case reports in the literature link SCLE to various types of cancer. This
review assesses the association between SCLE and neoplastic disorders. A PubMed search
was performed for all relevant publications on cancer-associated SCLE from 1982 to
2022. This review supports the hypothesis that SCLE should be considered a facultative
paraneoplastic phenomenon. It also emphasizes the importance of cancer screening in
patients presenting SCLE manifestations.
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Article info
Publication history
Published online: July 27, 2022
Edited by Lazar Andrada-LucianaIdentification
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© 2022 Elsevier Inc. All rights reserved.
