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Subacute cutaneous lupus erythematosus: A facultative paraneoplastic dermatosis

      Abstract

      Subacute cutaneous lupus erythematosus (SCLE) is a photosensitive dermatosis characterized by a non-scarring papulosquamous eruption and specific antibodies in the patient's serum. Genetic and environmental factors represent the leading causes of SCLE; however, several case reports in the literature link SCLE to various types of cancer. This review aims to assess the association between SCLE and neoplastic disorders. We searched PubMed for all relevant publications on cancer-associated SCLE from 1981 to 2022. This review supports the hypothesis that SCLE should be considered a facultative paraneoplastic phenomenon. It also emphasizes the importance of cancer screening in patients presenting SCLE manifestations.

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