Abstract
Annular skin lesions have a unique morphology, and the dramatic appearance of these
skin eruptions in infants can cause concern for parents and clinicians. Annular lesions
appearing during infancy (defined here as birth to 1 year of age) lend to a broad
differential, ranging from benign cutaneous disorders to severe systemic diseases.
This review summarizes the pathogenesis, clinical and histopathologic findings, and
management options of possible etiologies for annular skin lesions in infants, including
annular erythema of infancy, neonatal lupus erythematosus, dermatophyte infections,
hemorrhagic edema of infancy, and urticaria multiforme.
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Published online: February 02, 2022
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