Abstract
Although relatively uncommon, autoimmune bullous diseases carry the risk of increased
mortality and can significantly impact quality of life. This group of diseases is
broad and encompasses subepidermal conditions such as bullous pemphigoid, cicatricial
pemphigoid, epidermolysis bullosa acquisita, dermatitis herpetiformis, and linear
IgA bullous dermatosis, as well as intraepidermal conditions such as pemphigus and
its variants. The pathophysiology of each condition is incompletely understood but
broadly involves the formation of autoantibodies targeting skin adhesion proteins,
a process that relies on a complex interplay between a dysregulated immune system,
genetic predisposition, and environmental factors. We review the impact of nutrition
on pathogenesis, clinical course, and treatment of various autoimmune bullous diseases.
Key Words
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Published online: November 18, 2021
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