Hidradenitis suppurativa (HS) is a chronic, inflammatory, recurrent, debilitating
skin disease of the hair follicle characterized by painful, deep-seated, inflamed
lesions in the apocrine gland-bearing regions.
1
,2
Patients with HS have a higher comorbidity burden and a worse quality of life (QoL)
compared with patients affected by other skin diseases.
3
,
4
,
5
Anogenital involvement is associated with a high risk of complications, including
local scarring, anal/perianal fistulas, lymphedema, penile degloving, squamous cell
carcinoma, and the lack of efficacy for common systemic therapy.
4
,5
This brings a worse impact on QoL due to pain, secretions, and mobility issues.
4
,5
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References
- European S1 guideline for the treatment of hidradenitis suppurativa/acne inversa.J Eur Acad Dermatol Venereol. 2015; 29: 619-644
- Comparative overall comorbidity burden among patients with hidradenitis suppurativa.JAMA Dermatol. 2019; 155: 797-802
- Hidradenitis suppurativa: Epidemiology, clinical presentation, and pathogenesis.J Am Acad Dermatol. 2020; 82: 1045-1058
- Multidisciplinary update on genital hidradenitis suppurativa: A review.JAMA Surg. 2020; 155: 970-977
- Severe forms of hidradenitis suppurativa with complications in the anogenital area.Dermatol Ther. 2019; 32: e12910
Article info
Publication history
Published online: July 18, 2021
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© 2021 Elsevier Inc. All rights reserved.
