Abstract
Chemical peeling is a widely used procedure in the management of acne and acne scars.
It causes controlled destruction of a part of or the entire epidermis, with or without
the dermis, leading to exfoliation and removal of superficial lesions, followed by
regeneration of new epidermal and dermal tissues. The most frequently used peeling
agents are salicylic acid, glycolic acid, pyruvic acid, lactic acid, mandelic acid,
Jessner solution, trichloroacetic acid, and phenol. The appropriate peel is chosen
based on the patient’s skin type, acne activity, and type of acne scars. Combination
peels minimize side effects. In acne scars, chemical peels may be combined with other
procedures to achieve better clinical results. A series of chemical peels can lead
to significant improvement over a short period, leading to patient satisfaction and
maintenance of clinical results. © 2016 Elsevier Inc. All rights reserved.
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References
- Combination therapy in the management of atrophic acne scars.J Cutan Aesthet Surg. 2014; 7: 18-23
- Current state of acne treatment: highlighting lasers, photodynamic therapy, and chemical peels.Dermatol Online J. 2011; 17: 2
- Chemical peels for acne and acne scars in Asians: Evidence based review.J Cutan Aesthet Surg. 2012; 5: 239-246
- Acne scars: pathogenesis, classification and treatment.Dermatol Res Pract. 2010; 2010: 893080
- Salicylic acid peels for the treatment of acne vulgaris in Asian patients.Dermatol Surg. 2003; 29: 1196-1199
- Comparative study of oral isotretinoin versus oral isotretinoin +20% salicylic acid peel in the treatment of active acne.J Cutan Aesthet Surg. 2013; 6: 204-208
- Salicylic acid as a peeling agent for the treatment of acne.Cosmetic Dermatol. 1997; 10: 44-47
- Update on the treatment of acne vulgaris.J Clin Outcomes Manag. 2009; 16: 115-126
- Whitening effect of salicylic acid peels in Asian patients.Dermatol Surg. 2006; 32: 372-375
- Comparison of alpha- and beta-hydroxy acid chemical peels in the treatment of mild to moderately severe facial acne vulgaris.Dermatol Surg. 2008; 34: 45-50
- Glycolic acid chemical peeling improves inflammatory acne eruptions through its inhibitory and bactericidal effects on Propionibacterium acnes.J Dermatol. 2012; 39: 350-354
- Glycolic acid peeling in the treatment of acne.J Eur Acad Dermatol Venereol. 1999; 12: 119-122
- Expert opinion: efficacy of superficial chemical peels in active acne management—what can we learn from the literature today? Evidence-based recommendations.J Eur Acad Dermatol Venereol. 2011; 25: 695-704
- Glycolic acid versus Jessner’s solution: Which is better for facial acne patients? A randomized prospective clinical trial of split-face model therapy.Dermatol Surg. 1999; 25: 270-273
- Glycolic acid treatment increases type I collagen mRNA and hyaluronic acid content of human skin.Dermatol Surg. 2001; 27: 429-433
- The therapeutic value of glycolic acid peels in dermatology.Indian J Dermatol Venereol Leprol. 2003; 69: 148-150
- Glycolic acid peels versus salicylic-mandelic acid peels in active acne vulgaris and post-acne scarring and hyperpigmentation: a comparative study.Dermatol Surg. 2009; 35: 59-65
- Combination of microneedling and glycolic acid peels for the treatment of acne scars in dark skin.J Cosmet Dermatol. 2011; 10: 317-323
- Safety and efficacy of glycolic acid facial peel in Indian women with melasma.Int J Dermatol. 2001; 40: 354-357
- Alpha hydroxy acids: therapeutic potentials.Can J Dermatol. 1989; 1: 108-112
- Clinical and instrumental evaluation of skin improvement after treatment with a new 50% pyruvic acid peel.Dermatol Surg. 2006; 32: 526-531
- Introduction to cosmetic dermatology.Curr Probl Dermatol. 2003; 15: 43-83
- Lactic acid peeling in superficial acne scarring in Indian skin.J Cosmet Dermatol. 2010; 9: 246-248
- Efficacy of modified Jessner’s peel and 20% TCA versus 20% TCA peel alone for the treatment of acne scars.J Cutan Aesthet Surg. 2015; 8: 42-45
- The art of the trichloroacetic acid chemical peel.Clin Plast Surg. 1998; 25: 53-62
- Medium-depth chemical peels in the treatment of acne scars in dark-skinned individuals.Dermatol Surg. 2002; 28: 383-387
- Effective treatments of atrophic acne scars.J Clin Aesthet Dermatol. 2015; 8: 33-40
- Role of the 585-nm pulsed dye laser in the treatment of acne in comparison with other topical therapeutic modalities.J Cosmet Laser Ther. 2009; 11: 118-124
- Deep peeling using phenol versus percutaneous collagen induction combined with trichloroacetic acid 20% in atrophic post-acne scars: a randomized controlled trial.J Dermatolog Treat. 2014; 25: 130-136
- Focal treatment of acne scars with trichloroacetic acid: Chemical reconstruction of skin scars method.Dermatol Surg. 2002; 28: 1017-1021
- Histological study of depressed acne scars treated with serial high concentration (95%) trichloroacetic acid.Dermatol Surg. 2006; 32: 985-990
- Analysis of focal high concentration TCA treatment for atrophic acne scarring.Jap J Plast Reconstr Surg. 2006; 49: 573-653
- Trichloroacetic acid peels.Aesthet Surg J. 2004; 24: 469-470
- An assessment of the efficacy and safety of CROSS technique with 100% TCA in the management of ice pick acne scars.J Cutan Aesthet Surg. 2010; 3: 93-96
- Evaluation of CROSS technique with 100% TCA in the management of ice pick acne scars in darker skin types.J Cosmet Dermatol. 2011; 10: 51-57
- Platelet-rich plasma versus CROSS technique with 100% trichloroacetic acid versus combined skin needling and platelet rich plasma in the treatment of atrophic acne scars: a comparative study.Dermatol Surg. 2014; 40: 864-873
- Textbook of Chemical Peels: Superficial, Medium and Deep Peels in Cosmetic Practice.Informa Healthcare, London, UK2007: 206
- Effectiveness of modified phenol peel (Exoderm) on facial wrinkles, acne scars and other skin problems of Asian patients.J Dermatol. 2007; 34: 17-24
- Superficial chemical peels.J Cosmet Dermatol. 2006; 5: 246-253
- Chemical peels.Clin Dermatol. 2008; 26: 200-208
- Atrophic acne scarring: a review of treatment options.J Clin Aesthet Dermatol. 2015; 8: 50-58
- Severe hyperpigmentation and scarring following glycolic acid peel treatment in combination with low-dose isotretinoin.Eur J Med Res. 2014; 19: 60
- European evidence-based (S3) guidelines for the treatment of acne.J Eur Acad Dermatol Venereol. 2012; 26: 1-29
- Early chemabrasion for acne scars after treatment with oral isotretinoin.Dermatol Surg. 2012; 38: 1521-1526
- Dermabrasion for acne scars during treatment with oral isotretinoin.Dermatol Surg. 2010; 36: 483-489
Article info
Footnotes
☆Please submit contributions to the section to Eftychia Platsidaki, MD, at [email protected]
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© 2016 Elsevier Inc. All rights reserved.
