Abstract
Perioral dermatitis is a relatively common inflammatory facial skin disorder that
predominantly affects women. It is rarely diagnosed in children. A typical perioral
dermatitis presentation involves the eruption of papules and pustules that may recur
over weeks to months, occasionally with fine scales. The differential diagnosis includes
seborrheic dermatitis, systemic lupus erythematosus, acne vulgaris, lupus miliaris
disseminatus faciei, polymorphous light eruption, steroid-induced rosacea, granulomatous
perioral dermatitis, contact dermatitis (allergic and irritant), and even basal cell
carcinoma. The histopathology is similar to that of rosacea, with a perivascular and
perifollicular lymphohistiocytic infiltrate and sebaceous hyperplasia. The etiology
of perioral dermatitis is unknown, but the uncritical use of topical corticosteroids
often precedes skin lesions. Physical sunscreens with high sun protection factors
may cause perioral dermatitis in children.
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References
- Perioral dermatitis.Clin Dermatol. 2011; 29: 157-161
- Light-sensitive seborrheid.Arch Dermatol. 1957; 75: 245-248
- Perioral dermatitis.in: Wolff K. Goldsmith L.A. Katz S.I. Gilchrest B.A. Paller A.S. Leffell D.J. Fitzpatrick's Dermatology in General Medicine. 7th ed. McGraw Hill Medical, New York2008: 709-712
- Perioral dermatitis in childhood.J Am Acad Dermatol. 1992; 27: 688-692
Kammler H. Perioral dermatitis. E-medicine. Available at http://www.emedicine.com/derm/topic321.htm. Accessed October 8, 2010.
- Steroid dermatitis resembling rosacea-etiopathogenesis and treatment.J Eur Acad Dermatol Venereol. 2002; 16: 121-126
- Perioral dermatitis.Acta Dermatovenerolol Croat. 2008; 16: 96-100
- Topical cosmetics and perioral dermatitis.J Dtsch Dermatol Ges. 2004; 2: 194-199
- Pemphigus of the eyelids.Eur J Dermatol. 2001; 11: 141-143
- Physical sunscreens with high sun protection factor may cause perioral dermatitis in children.J Dtsch Dermatol Ges. 2009; 7: 701-703
- Density of Demodex folliculorum in perioral dermatitis.Acta Derm Venereol. 2005; 85: 211-215
- Perioral dermatitis.Br J Dermatol. 1972; 87: 430-434
- Impaired skin barrier and atopic diathesis in perioral dermatitis.J Dtsch Dermatol Ges. 2003; 1: 199-203
- Histologic Diagnosis of Inflammatory Skin Diseases.Lea & Febiger, Philadelphia1978 (803–805)
- Clinical and histological study of a case of facial Afro-Caribbean childhood eruption (FACE).Ann Dermatol Venereol. 2008; 135: 663-667
- Epithelial barrier function and atopic diathesis in rosacea and perioral dermatitis.Br J Dermatol. 2004; 150: 1136-1141
- Childhood granulomatous periorificial dermatitis: lupus miliaris disseminatus faciei in children?.J Eur Acad Dermatol Venereol. 2005; 19: 470-473
- Acne agminata limited to the eyelids.Ophthal Plast Reconstr Surg. 2009; 25: 409-411
- Circumocular exanthema associated with chronic rejection after kidney transplantation.Prog Transplant. 2010; 20: 318-319
- Oral and perioral endogenous pigmented lesions.Rev Med Chir Soc Med Nat Iasi. 2008; 112: 1054-1060
- Perioral dermatitis in a patient with myasthenia gravis following systemic corticosteroid treatment.Br J Dermatol. 2007; 156: 582
- Cheilitis caused by contact urticaria to mint flavoured toothpaste.Australas J Dermatol. 2001; 42: 43-45
- Miliary and agminated-type primary cutaneous follicle center lymphoma: report of 18 cases.J Am Acad Dermatol. 2011; 65: 749-755
- Topical corticosteroid “addiction”: a cause of perioral dermatitis.Postgrad Med. 1993; 93: 225-230
- The treatment of steroid-induced rosacea and perioral dermatitis.Dermatologica. 1976; 152: 231-237
- Topical metronidazole in the treatment of perioral dermatitis.J Am Acad Dermatol. 1991; 87: 425-429
- Tacrolimus ointment for the treatment of steroid induced rosacea: a preliminary report.J Am Acad Dermatol. 2001; 44: 995-998
- A randomized, double-blind, vehicle-controlled study of 1% pimecrolimus cream in adult patients with perioral dermatitis.J Am Acad Dermatol. 2008; 59: 34-40
- Photodynamic therapy for perioral dermatitis.J Drugs Dermatol. 2006; 5: 12-16
- Periocular milia en plaque successfully treated by erbium:YAG laser ablation.J Cosmet Laser Ther. 2011; 13: 35-37
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