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Research Article| Volume 6, ISSUE 4, P213-217, October 1988

Three percent topical minoxidil therapy for female androgenetic alopecia

  • Maria K. Hordinsky
    Correspondence
    Address for correspondence: Maria K. Hordinsky, MD, Department of Dermatology, University of Minnesota School of Medicine, Box 98 UMHC/4-240 PWB, 420 Delaware Street SE, Minneapolis, MN 65455-0392.
    Affiliations
    From the Department of Dermatology, University of Minnesota School of Medicine, Minneapolis, Minnesota USA
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  • Judith Shank
    Affiliations
    From the Department of Dermatology, University of Minnesota School of Medicine, Minneapolis, Minnesota USA
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      Abstract

      Effective treatment of female androgenetic alopecia involves cessation of hair shedding and promotion of normal anagen hair growth. The topical use of hormones such as progesterone or an androgen receptor-binding drug such as spironolactone has not been associated with significant hair regrowth.1 In contrast, the topical use of minoxidil has resulted in decreased hair shedding and hair growth promotion, particularly in men with androgenetic alopecia.2 To investigate the usefulness of topical minoxidil therapy in female androgenetic alopecia, we studied the efficacy and safety of 3% topical minoxidil in 25 affected women. Results were correlated with disease extent and activity.
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