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Abstract
By means of increasingly more penetrating research efforts, the pharmaceutical industry
is acquiring ever greater insight into disease and other adverse processes. This results
in the discovery and development of drugs with more highly complex actions. This,
together with a more stringent surveillance by government regulatory agencies, has
increased the time required to develop a newly discovered entity from a few years
in the 1950s and early 1960s to as much as 10–12 years at the present time. In cases
where serendipitous discovery of new opportunities results in added dimensions for
pursuit, the time required is even greater. The development of minoxidil as an agent
to reverse androgenetic alopecia, now being concluded after 27 years, characterizes
this more elaborate process.
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© 1988 Published by Elsevier Inc.
