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Research Article| Volume 6, ISSUE 4, P108-118, October 1988

The comparative histopathology of male-pattern baldness and senescent baldness

  • Albert M. Kligman
    Correspondence
    Address for correspondence: Albert M. Kligman, MD, PhD, University of Pennsylvania School of Medicine, Department of Dermatology, Room 244, 36th and Hamilton Walk/GM, Philadelphia, PA 19104.
    Affiliations
    From the Department of Dermatology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania USA
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      Abstract

      Although knowledge of normal scalp anatomy, the hair follicle, and the dynamics of hair cycling is substantial,1–3 the histopathology of male-pattern baldness (MPB), also called premature baldness or androgenetic alopecia, is uncertain. Textbook accounts are uninformative,4,5 and controversies are plentiful. Disputes exist about matters that seem quite simple, for example, whether the sebaceous glands are enlarged or shrunken. There are also opposing views on the fate of the arrector pili muscles. All agree that hair follicles become progressively smaller (miniaturized), but whether there is an actual loss of follicles is in contention. Two important publications on various cutaneous aspects of aging do not even include chapters on hair.6,7
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