This paper is only available as a PDF. To read, Please Download here.
Abstract
Although knowledge of normal scalp anatomy, the hair follicle, and the dynamics of
hair cycling is substantial,1–3 the histopathology of male-pattern baldness (MPB), also called premature baldness
or androgenetic alopecia, is uncertain. Textbook accounts are uninformative,4,5 and controversies are plentiful. Disputes exist about matters that seem quite simple,
for example, whether the sebaceous glands are enlarged or shrunken. There are also
opposing views on the fate of the arrector pili muscles. All agree that hair follicles
become progressively smaller (miniaturized), but whether there is an actual loss of
follicles is in contention. Two important publications on various cutaneous aspects
of aging do not even include chapters on hair.6,7
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to Clinics in DermatologyAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- The Structure and Function of Skin.in: 2nd ed. Academic Press, New York1962: 96-101
- Aging of the human scalp.in: Montagna W Ellis RA The Biology of Hair Growth. Academic Press, New York1958: 469-473
- The human hair cycle.J Invest dermatol. 1959; 33: 307-316
- Disorders of epidermal appendages.in: Fitzpatrick TB Eisen AZ Wolff K Dermatology in General Medicine. 3rd ed. McGraw-Hill, New York1987: 635-651
- Diseases of the Hair and Scalp.in: Blackwell Scientific Publications, Oxford1982: 140-148
- Aging in advances in biology of skin.J Invest dermatol. 1979; 73: 1-13
- Skin and Aging Processes.CRC Press, Boca Raton1984
- The pre-natal and post-natal hair cycles in man.in: Baccaredda-Boy A Moretti G Frey JR Biopathology of Pattern Alopecia. Karger, Basel1968: 29-38
- Age changes in cutaneous appendages.J Appl Cosmetol. 1985; 3: 243-250
- Common baldness in women.in: Seminars in Dermatology. 4. 1985: 1-12
- Transverse microscopic anatomy of the human scalp.Arch dermatol. 1984; 120: 449-456
- Anatomie der Haut: Handbuch der Haut und Geschlechtskrankheiten.in: Springer-Verlag, New York1927: 213-217
- The environment of the hair follicles.in: Orfanos CE Montagna W Stuttgen G Hair Research. Status and Future Aspects. Springer-Verlag, Berlin1981: 172-177
- Connective tissue hair sheath, especially on the structure and development elastic tissues.in: Kobori T Montagna W Biology and Diseases of the Hair. University Park Press, Baltimore1976: 214-218
- Epithelial-mesodermal interaction in normal hair growth, alopecia and neoplasia.J dermatol. (Tokyo). 1978; 5: 93-101
- Biology of hair growth.Semin Reprod Endocrinol. 1986; 4: 131-141
- Human hair cycle.J Invest dermatol. 1970; 54: 65-73
- Hair neogenesis in man. A histoquantitative study based on 1000 scalp biopsies.in: Orfanos CE Montagna W Stuttgen G Hair Research. Status and Future Aspects. Springer-Verlag, Berlin1981: 344-352
- Histology and histochemical aspects of the hair follicles in pattern alopecia.in: Baccaredda-Boy A Moretti G Frey JR Biopathology of Pattern Alopecia. Karger, Basel1968: 107-111
- Male pattern alopecia: a histopathological and histochemical study.J Cutan Pathol. 1975; 2: 58-64
- Clinical and histologic studies of male pattern baldness treated with topical minoxidil.Curr Ther Res. 1984; 36: 1098-1106
- The histopathology of common male baldness.in: Excerpta Med Internal Congress Series. 55. 1962: 1438-1441
- Alopecia: clinicopathologic correlations.Int J dermatol. 1980; 19: 245-253
- Evaluation of disturbed hair growth in alopecia areata and other alopecias.Ann NY Acad Sci. 1959; 83: 480-490
- Size and shape of sebaceous glands in male pattern alopecia.in: Baccaredda-Boy A Moretti G Frey JR Biopathology of Pattern Alopecia. Karger, Basel1968: 155-158
- The anatomy of the human scalp.in: Advances in Biology of Skin. Vol.VI. Appleton-Century-Crofts, New York1965: 97-111
- Pelades et Alopecies en Aires.in: Masson et Cie, Paris1929: 114-118
Article info
Identification
Copyright
© 1988 Published by Elsevier Inc.