Research Article| Volume 6, ISSUE 4, P67-73, October 1988

The hair cycle and its regulation

  • F.John G. Ebling
    Address for correspondence: John Ebling, DSc, PhD, Sub-Department of Dermatology, Academic Division of Medicine, University of Sheffield, Royal Hallamshire Hospital, Sheffield, S10 2JF, England.
    From the University of Sheffield, Royal Hallamshire Hospital, Sheffield, England
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      The most important feature of hair growth is the cyclic activity of hair follicles in which an active phase, anagen, is succeeded by a resting phase, telogen, during which the fully formed hair remains anchored in the follicle. Between anagen and telogen there is a short transitional phase called catagen. In 1924, Trotter1 recognized that such a cycle existed in man. Two years later, Dry2 described the cycle in detail for the mouse and first used the terminology, which currently is universally accepted. A detailed account of the hair cycle in the human scalp, however, awaited the work of Kligman in 1959.3 Today, his pictures still provide classic illustrations of the sequence of events.
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