Clinics in Dermatology
Volume 27, Issue 6, Supplement , Pages S41-S43 , November 2009

Evaluation of a nonsteroidal topical cream in a guinea pig model of Malassezia furfur infection

  • Vijendra Nalamothu

      Affiliations

    • Research and Development, Promius Pharma, LLC, Bridgewater, NJ 08807, USA
    • Corresponding Author InformationCorresponding author. Tel.: +1 908 203 4952.
    • Mr Nalamothu is an employee of Promius Pharma, LLC.
    • ,
  • Ann L. O'Leary, PhD

      Affiliations

    • Ricerca Biosciences, LLC, Concord, OH 44077, USA
    • ,
  • Sateesh Kandavilli, PhD

      Affiliations

    • Research and Development, Promius Pharma, LLC, Bridgewater, NJ 08807, USA
    • ,
  • Joanne Fraser, PhD

      Affiliations

    • Research and Development, Promius Pharma, LLC, Bridgewater, NJ 08807, USA
    • ,
  • Vishvabhavan Pandya, MD

      Affiliations

    • Research and Development, Promius Pharma, LLC, Bridgewater, NJ 08807, USA

References 

  1. Bikowski J. Facial seborrheic dermatitis: a report on current status and therapeutic horizons. J Drugs Dermatol. 2009;8:125–133
  2. Midgley G. The lipophilic yeasts: state of the art and prospects. Med Mycol. 2000;38(Suppl 1):9–16
  3. Malassez L. Note sur le champignon du pityriasis simple. Arch Physiol. 1974;2:451–464
  4. Shuster S. The aetiology of dandruff and the mode of action of therapeutic agents. Br J Dermatol. 1984;3:235–242
  5. Skinner RB, Noah PW, Taylor RM, et al. Double-blind treatment of seborrheic dermatitis with 2% ketoconazole cream. J Am Acad Dermatol. 1985;12:852–856
  6. Zisova LG. Malassezia species and seborrheic dermatitis. Folia Med (Plovdiv). 2009;51:23–33
  7. Van Gerven F, Odds FC. The anti-Malassezia furfur activity in vitro and in experimental dermatitis of six imidazole antifungal agents: bifonazole, clotrimazole, flutrimazole, ketoconazole, miconazole and sertaconazole. Mycoses. 1995;38:389–393
  8. Van Cutsem J, Van Gerven F, Fransen J, Schrooten P, Janssen PAJ. The in vitro antifungal activity of ketoconazole, zinc pyrithione, and selenium sulfide against Pityrosporum and their efficacy as shampoo in the treatment of experimental pityrosporosis in guinea pigs. J Am Acad Dermatol. 1990;22:993–998
  9. Leeming JP, Notman FH. Improved methods for isolation and enumeration of Malassezia furfur from human skin. J Clin Microbiol. 1987;25:2017–2019
  10. Miranda KC, de Araujo CR, Costa CR, Passos XS, Fernandes OFL, Silva MRR. Antifungal activities of azole agents against the Malassezia species. Int J Antimicrob Agents. 2007;29:281–284
  11. Bergbrant IM. Seborrhoeic dermatitis and Pityrosporum yeasts. Curr Top Med Mycol. 1995;6:95–112
  12. Faergemann J. Pityrosporum infections. 2nd ed.. Malden (Mass): Blackwell Science; 1998;
  13. Ashbee HR, Evans EG. Immunology of diseases associated with Malassezia species. Clin Microbiol Rev. 2002;15:21–57
  14. Gupta AK, Bluhm R. Seborrheic dermatitis. J Eur Acad Dermatol Venereol. 2004;18:13–26

PII: S0738-081X(09)00193-X

doi: 10.1016/j.clindermatol.2009.09.003

Clinics in Dermatology
Volume 27, Issue 6, Supplement , Pages S41-S43 , November 2009

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