Clinics in Dermatology
Volume 26, Issue 4 , Pages 334-340 , July 2008

Chitin nanofibrils for advanced cosmeceuticals

  • Pierfrancesco Morganti, PhD

      Affiliations

    • Applied Cosmetic Dermatology, II University of Naples, Naples, Italy
    • Skin Pharmacology, China Medical University, Shenyang, China
    • Mavi Sud srl, Viale Dell'industria 1, 04011 Aprilia (LT), Italy
    • ,
  • Gianluca Morganti, PhD

      Affiliations

    • Mavi Sud srl, Viale Dell'industria 1, 04011 Aprilia (LT), Italy
    • Corresponding Author InformationCorresponding author. Mavi Sud srl, Viale Dell'industria 1, 04011 Aprilia (LT), Italy. Tel.: +36 0 6 92862626; fax: +39 0 6 9281523.

References 

  1. Raabe D, Romano P, Sachs C, et al. Microstructure and crystallographic texture of the chitin-protein network in the biological composite material of the exoskeleton of the lobster Homarus americanus. Mater Sci Eng A Struct Mater. 2006;421:143–153
  2. Belamie E, Davidson P. Giraud-Guille, Structure and chirality of the nematic phase in alpha-chitin suspensions. J Phys Chem B. 2004;108:14991–15000
  3. Raabe D, Romano P, Sachs C, et al. Discovery of a honeycomb structure in the twisted plywood patterns of fibrous biological nanocomposite tissue. J Cryst Growth. 2005;283:1–7
  4. Muzzarelli RAA, Muzzarelli C. Chitin nanofibrils. In:  Dutta PK editors. Chitin and chitosan: research opportunities and challenges. New Delhi, India: New Age Intl; 2005;
  5. Li J, Revol JF, Naranjo E, Marchessault RH. Effect of the degree of deacetylation of chitin on the properties of chitin crystallites. J Appl Polym Sci. 1997;65:373–380
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  7. Jollès P, Muzzarelli RAA. Chitin and chitinases. Basel: Birkhauser; 1999;
  8. MAVI Patent Pending 2006.
  9. Morganti P, Muzzarelli RAA, Muzzarelli C. Multifunctional use of innovative chitin derivatives for skin care. J Appl Cosmetol. 2006;24:105–114
  10. Fischer TK, Thatte HS, Nichols TC, Bender-Neal DE, Bellinger DA, Vournakis JN. Synergistic platelet integrin signaling and factor XII activation in poly-N-acetyl glucosamine fiber-mediated hemostasis. Biomaterials. 2005;27:543
  11. Chan MW, Schwaitzberg SD, Demcheva M, Vournakis J, Finkielsztein S, Connolly RJ. Comparison of poly-N-acetyl glucosamine with absorbable collagen (Actifoam), and fibrin sealant (Bolheal) for achieving hemostasis in a swine model of splenic hemorrhage. J Trauma. 2000;48:454–457
  12. Kössi J, Vähä-Kreula M, Peltonen S, Risteli J, Laato M. Effect of sucrose on collagen metabolism in keloid, hypertrophic scar, and granulation tissue fibroblast cultures. World J Surg. 2001;25:142–146
  13. Adams M. About glucosamine. Lancet. 1999;354:353–354
  14. Berra B. Glucosamina. In:  Rapport C,  Lockwood B editor. Nutraceuticals. Milano, Italy: MDM Medical Media; 2003;p. 17–29
  15. Morganti P, Muzzarelli RAA, Muzzarelli C, e Morganti G. Chitin nanofibrils: a natural compound for innovative cosmeceuticals. C&T. 2007;122:81–88
  16. Muzzarelli RAA, Morganti P, Morganti G, et al. Chitin nanofibrils/chitosan glycolate composites as wound medicaments. Carbohydrate Polymers. 2007;70:274–284
  17. Kulling D, Vournakis JN, Woo S, et al. Endoscopic injection of bleeding esophageal varices with a poly-N-acetyl glucosamine gel formulation in the canine portal hypertension model. Bull Gastroint Endosc. 1999;49:764–771
  18. Shibata Y, Foster LA, Metzger WJ, Myrvik QN. Alveolar macrophage priming by intravenous administration of chitin particles, polymers of N-acetyl-D-glucosamine, in mice. Infect Immun. 1997;65:1734–1741
  19. Morganti P, Muzzarelli RAA, Muzzarelli C, Morganti G. Le nanofibrille di chitina una realtà tutta italiana. Cosmet Technol. 2006;9:21–25
  20. COM 2005. Trend Chart Innovation Policy. Available at: http://trendchart.cordis.lu/.
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PII: S0738-081X(08)00004-7

doi: 10.1016/j.clindermatol.2008.01.003

Clinics in Dermatology
Volume 26, Issue 4 , Pages 334-340 , July 2008

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