Clinics in Dermatology
Volume 26, Issue 3 , Pages 296-305, May 2008

Hair, nail, and pigment changes in major systemic disease

Sector of Dermatology and Post-Graduation Course, University Hospital and School of Medicine, Federal University of Rio de Janeiro, 22280-020 Rio de Janeiro, Brazil

Abstract 

In this article, the nail, hair, and pigment changes caused by systemic diseases will be reviewed. Among the subjects discussed are abnormalities of shape, attachments, surface, and color of the nails; hair alterations such as telogen and anagen effluvium, scarring alopecia, hypertrichosis, and hirsutism; and pigment changes due to connective tissue disorders, sarcoidosis, and metabolic and endocrinologic diseases, among others.

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PII: S0738-081X(07)00242-8

doi:10.1016/j.clindermatol.2007.10.019

Clinics in Dermatology
Volume 26, Issue 3 , Pages 296-305, May 2008