Clinics in Dermatology
Volume 24, Issue 2 , Pages 109-112 , March 2006

Herpes gestationis (Pemphigoid gestationis)

  • Abdul-Wahab S. Al-Fouzan, MD

      Affiliations

    • Department of Dermatology, Al-Sabah Hospital, PO Box 1161, Safat-13002, Kuwait
    • Corresponding Author InformationCorresponding author. Department of Dermatology, Al-Sabah Hospital, PO Box 1161, Safat-13002, Kuwait. Tel.: +965 2666120; fax: +965 2666121.
    • ,
  • Ibrahim Galadari, MD

      Affiliations

    • Dermatology Department, United Arab Emirates University, Dubai, UAE
    • ,
  • Isam Oumeish, MD

      Affiliations

    • Department of Dermatology, King Hussein Medical Center, 11831 Amman, Jordan
    • ,
  • Oumeish Y. Oumeish, MD

      Affiliations

    • Department of Dermatology, Tulane University School of Medicine, New Orleans, LA 70112-2632, USA

References 

  1. Provost TT, Tomasi TB. Evidence of complement activation via the alternate pathway in skin diseases: 1. Herpes gestationis, systemic lupus erythematosus and bullous pemphigoid. J Clin Invest. 1973;52:1779–1787
  2. Morrison LH, Anhalt GJ. Herpes gestationis. J Autoimmun. 1991;4:37–45
  3. Shornick JD. Dermatoses of pregnancy. Semin Cutan Med Surg. 1998;17:172–181
  4. Shornick JK, Black MM. Secondary autoimmune diseases in herpes gestationis. J Am Acad Dermatol. 1992;26:563–566
  5. Kelly SE, Cerio R, Bhogal BS, Bluck MM. The distribution of IgG subclasses in pemphigoid gestationis PG factor is an IgG autoantibody. J Invest Dermatol. 1989;92:695–698
  6. Scheman AJ, Hordinsky MD, Groth DW, Vercellotti GM, Leiferman KM. Evidence of eosinophil degranulation in the pathogenesis of herpes gestationis. Arch Dermatol. 1989;125:1079–1083
  7. Kelly SE, Bhogal BS, Wojnarowska F, Black MM. Expression of a pemphigoid gestationis–related antigen by human placenta. Br J Dermatol. 1988;118:605–611
  8. Engineer L, Bhol K, Ahmed AR. Pemphigoid gestationis: a review. Am J Obstet Gynecol. 2000;183:483–491
  9. Yancey KB. Herpes gestationis. Dermatol Clin. 1969;104:39–45
  10. Jankins RE, Hern S, Black MM. Clinical features and management of 87 patients with pemphigoid gestationis. Clin Exp Dermatol. 1999;24:255–259
  11. Shornick JK. Herpes gestationis. J Am Acad Dermatol. 1987;17:539–556
  12. Baxmi LV, Kovilam OP, Collins MH, Walter RR. Recurrent herpes gestationis with postpartum flare: a case report. Am J Obstet Gynecol. 1998;164:778–780
  13. Holmes RC, Black MM, Williamson DM, Sutt RWB. Herpes gestationis and bullous pemphigoid: a disease spectrum. Br J Dermatol. 1988;103:535–541
  14. Shornick JK, Banger JK, Freeman RG, Gilliam JN. Herpes gestationis: clinical and histologic features in 28 cases. J Am Acad Dermatol. 1993;8:214–224
  15. Holmes RC, Williamson DM, Black MM. Herpes gestationis persisting for 12 years postpartum. Arch Dermatol. 1986;122:375–376
  16. Shornick JK. Pregnancy dermatoses. In:  Bolognia JL,  Jorizzo JL,  Rapini RP editor. Dermatology textbook. vol 1:Mosby; 2003;p. 428
  17. Powell M, Sakuma-Oyama Y, Oyama N, et al. Usefulness of BP180 NC16a ELISA in the serodiagnosis of pemphigoid gestationis (HG) and in differentiating between HG and PUPPP. Arch Dermatol. 2005;141:705–710
  18. Pőnnighaws JM, Ziegler H, Kowalzick L. Herpes gestationis: oral corticosteroids cannot be avoided. Zentralbl Gynakol. 1998;120:548–550[German]
  19. Lawley JJ, Stingl G, Katz SI. Fetal and maternal risk factors in herpes gestationis. Arch Dermatol. 1979;114:552–555
  20. Jenkins RE, Shornick JK, Black MM. Pemphigoid gestationis. J Eur Acad Dermatol Vener. 1993;2:163–173
  21. Yancy KB. Herpes gestationis. Dermatol Clin. 1990;8:727–734
  22. Jenkins RE, Hern S, Black MM. Clinical features and management of 87 patients with pemphigoid gestationis. Clin Exp Dermatol. 1999;24:255–259
  23. Fine JD, Omura EF. Herpes gestationis. Persistent disease activity 11 years post partum. Arch Dermatol. 1985;121:924–926
  24. Castle SP, Mather-Mondroy M, Bennion S, David Bajar K, Huff K. Chronic herpes gestationis and antiphospholipid antibody syndrome successfully treated with cyclophosphamide. J Am Acad Dermatol. 1995;34:333–336
  25. Hocking DR. Neonatal haemolytic disease due to dapsone. Med J Aust. 1968;i:1130–1131
  26. Karna P, Broeker AH. Neonatal herpes gestationis. J Pediatr. 1991;119:299–301
  27. Shornick JK, Black MM. Fetal risks in herpes gestationis. J Am Acad Dermatol. 1992;26:63–68

PII: S0738-081X(05)00129-X

doi: 10.1016/j.clindermatol.2005.10.011

Clinics in Dermatology
Volume 24, Issue 2 , Pages 109-112 , March 2006

Article Tools

* Image Usage & Resolution